Should content creators focus on advertiser-friendly content?

CPM (Cost Per Milli) is the revenue multiplier for different categories of content. For example, pharma related content would have a higher CPM than entertainment related content.

The incentives are skewed towards certain types of content, so this pushed creators to make advertiser friendly content or high-CPM content. Is the vacuum filled by other types of creators? Does the free-market balance out the opportunities or are some industries that need more creators?